Interleukin-1 (IL-1) Market by Type (Anakinra, Rilonacept, Canakinumab, and Gintuit), and Application (Arthritis and Inflammatory Diseases) – Market Size & Forecast, 2019-2030

Report ID : 215  |  Published Date : Feb 2020  |  Pages : 170  |  Region : Global  |  Report Code : PH-14





Interleukin-1 (IL-1) Market Overview and Introduction               

Interleukin-1 (IL-1) constitutes of a group of 11 cytokines, which play a vital role in regulating inflammatory & immune response against infections. The family of Interleukin-1 (IL-1) majorly constitutes of two distinct proteins, viz. IL-1 beta and IL-1 alpha. The functionality of IL-1 is not only limited to inflammation, but it also plays a role in regulating insulin secretion & fever, bone remodeling & formation, and neuronal phenotype development among others. IL-1 is an extremely active pro-inflammatory cytokine which significantly increases pain thresholds. The mono-therapeutic blockage of IL-1 activity in auto-inflammatory syndromes, considerably reduces pain and severity of the disease.  

IL-1 plays a crucial role in neuroinflammation. During an episode of inflammation, the quantity of IL-1 increases significantly, which in turn increases the chances of breakdown of the blood-brain barrier. Therapeutic application of blocking agents or drugs, blocks the biological activity of IL-1, which leads to swift improvement in clinical symptoms. The growth of the Interleukin-1 market can be attributed to the efficacy of the drug, as its application extensively improves inflammation and symptoms for conditions such as rheumatoid arthritis, immune-mediated inflammatory conditions, and other forms of autoinflammatory diseases. Moreover, rising cases of arthritis and strong product pipeline of IL-1 drugs by major pharmaceutical manufacturers are few of the other factors contributing to the significant growth of the global Interleukin-1 market. However, probability of serious allergic reactions such as anaphylactic reactions, may hinder the global Interleukin-1 market to a certain extent.

The global Interleukin-1 (IL-1) market is majorly classified into three segments, viz. by type, application, end user and region.

Interleukin-1 (IL-1) Market by Type

The segment of type can be classified into the following categories, anakinra, rilonacept, canakinumab, gintuit and other types

Interleukin-1 (IL-1) Market by Application

On the basis of application, the Interleukin-1 (IL-1) market is bifurcated into, arthritis, inflammatory diseases and other applications (type 2 diabetes, epilepsy, & cancer).

Interleukin-1 (IL-1) Market by Region

The global Interleukin-1 (IL-1) market can be segmented into North America, Asia Pacific, Europe and Rest of World (ROW). The global Interleukin-1 (IL-1) market is driven by rising cases of orthopedic ailments, such as osteoarthritis, rheumatoid arthritis and other disorders such as periodic fever syndromes such as Cryopyrin-Associated Periodic Syndrome (CAPS), Neonatal-Onset Multisystem Inflammatory Disease (NOMID) and Tumor Necrosis Factor Receptor-Associated Periodic Syndrome (TRAPS) among others.

Interleukin-1 (IL-1) Market Prominent Players

The prominent players operating in the global Interleukin-1 (IL-1) market are Swedish Orphan Biovitrum AB, Regeneron Pharmaceuticals, Inc., Novartis AG, Vertex Pharmaceuticals Incorporated, XBiotech, Creative Biolabs and other prominent players.

Table of Contents

  1. INTRODUCTION
    1. Market Definition
    2. Market Classification
    3.  Geographic Scope
    4.  Years Considered for the Study: Historical Years – 2016 & 2017; Base Year – 2018; Forecasted Years – 2019 to 2030
    5. Currency Used
  2. RESEARCH METHODOLOGY
    1. Research Framework                              
    2. Data Collection Technique
    3. Data Sources
      1.  Secondary Sources
      2.  Primary Sources
    4. Market Estimation Methodology
      1.  Bottom Up Approach
      2.  Top Down Approach
    5. Data Validation and Triangulation
      1.  Market Forecasting Model
      2.  Limitations/Assumptions of the Study
  3. ABSTRACT OF THE STUDY
  4. MARKET DYNAMICS ASSESMENT
    1. Overview
    2. Drivers
    3. Barriers/Challenges
    4. Opportunities
  5. UNIQUE SELLING PROPOSITIONS (USPs)
    1. Pipeline Assessment
    2. Epidemiological Assessment: Arthritis, Cancer & Others
  6. GLOBAL INTERLEUKIN 1 (IL1) MARKET - ANALYSIS & FORECAST, BY TYPE
    1. Anakinra
    2. Rilonacept
    3. Canakinumab
    4. Gintuit
    5. Other Types
  7. GLOBAL INTERLEUKIN 1 (IL1) MARKET - ANALYSIS & FORECAST, BY APPLICATION
    1. Arthritis
    2. Inflammatory Diseases
    3. Other Applications (Type 2 Diabetes, Epilepsy, & Cancer)
  8. GLOBAL INTERLEUKIN 1 (IL1) MARKET - ANALYSIS & FORECAST, BY REGION
    1.   North America Interleukin 1 (IL1) Market    
      1.  North America Interleukin 1 (IL1)  Market, By Country
        1.  US        
        2.  Canada                               
      2. North America Interleukin 1 (IL1) Market Analysis & Forecast, By Type
      3. North America Interleukin 1 (IL1) Market Analysis & Forecast, By Application
    2. Europe Interleukin 1 (IL1) Market
      1. Europe Interleukin 1 (IL1)  Market, By Country/Region
        1. Germany
        2. U.K
        3. France
        4. Rest of Europe (ROE)
      2. Europe Interleukin 1 (IL1) Market Analysis & Forecast, By Type
      3. Europe Interleukin 1 (IL1) Market Analysis & Forecast, By Application
    3. Asia Pacific Interleukin 1 (IL1) Market
      1. Asia Pacific Interleukin 1 (IL1) Market, By Country/Region
        1. China
        2. Japan
        3. India
        4. Rest of Asia Pacific (RoAPAC)
      2. Asia Pacific Interleukin 1 (IL1) Market Analysis & Forecast, By Type
      3. Asia Pacific Interleukin 1 (IL1) Market Analysis & Forecast, By Application
    4.   Rest of the World (ROW) Interleukin 1 (IL1) Market
      1. Rest of the World Interleukin 1 (IL1)  Market, By Country/ Region
        1.  Latin America   
        2.  Middle East & Africa
      2. Rest of the World Interleukin 1 (IL1) Market Analysis & Forecast, By Type
      3. Rest of the World Interleukin 1 (IL1) Market Analysis & Forecast, By Application
  9. COMPETETIVE LANDSCAPE
    1. Key Players & Their Competitive Positioning (2018)
    2. Key Strategies Assessment
      1. New Product Launches
      2. Merger & Acquisitions
      3. Agreements, Collaborations, & Partnerships
      4. Expansions
      5. Other Strategies
  10. COMPANY PROFILES              (Business Overview, Products Offered, Financial Performance, Recent Developments)*
    1.  Swedish Orphan Biovitrum AB
    2.  Regeneron Pharmaceuticals, Inc.
    3.  Novartis AG
    4.  Vertex Pharmaceuticals Incorporated
    5.  XBiotech
    6.  Creative Biolabs
    7.  Other Prominent Players                       *Financial details might not be captured in case of privately-held companies or for companies that do not report this information in public domain